bs-3980R FBP1-抗体-抗体-生物在线
北京索莱宝科技有限公司
bs-3980R FBP1

bs-3980R FBP1

商家询价

产品名称： bs-3980R FBP1

英文名称： FBP1

产品编号： bs-3980R

产品价格： null

产品产地： 北京

品牌商标： BIOSS

更新时间： 2025-12-22T13:21:18

使用范围： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,

北京索莱宝科技有限公司
  • 联系人 : 索莱宝-龚思雨
  • 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
  • 邮编 :
  • 所在区域 : 北京
  • 电话 : 181****6239 点击查看
  • 传真 : 点击查看
  • 邮箱 : 3193328036@qq.com
  • 二维码 : 点击查看
进入展台

Beijing solarbio science ＆technology CO.,LTD
北京索莱宝科技有限公司  张净花  010-56371206
北京索莱宝科技有限公司  张净花  13426459985
http://solarbio.bioon.com.cn/
产品编码   bs-3980R
英文名称 FBP1
中文名称 果糖1，6-二***酶抗体
别    名 6-bisphosphatase 1; 6-bisphosphate 1-phosphohydrolase 1; D fructose 1 6 bisphosphate 1 phosphohydrolase 1; D-fructose-1; EC 3.1.3.11; F16P1_HUMAN; FBP; FBP 1; FBP1; FBPase 1; Fructose 1 6 bisphosphatase 1; Fructose bisphosphatase 1; Fructose-1; Growth inhibiting protein 17; Liver fructose bisphosphatase.
研究领域 肿瘤  细胞生物  免疫学  染色质和核信号  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
   
PubMed PubMed
产品介绍 background:
FBP1 is a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.ACLP2 (acid phosphatase-like 2), also known as UNQ370 or PRO706, is a 480 amino acid secreted protein that functions to catalyze the H2O-dependent conversion of a phosphate monoester to an alcohol and a phosphate. Expressed as two alternatively spliced isoforms, ACPL2 is encoded by a gene that maps to chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. 

Subunit:
Homotetramer. 

Tissue Specificity:
Belongs to the FBPase class 1 family.

DISEASE:
Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.

Similarity:
Belongs to the FBPase class 1 family. 

Database links:
UniProtKB/Swiss-Prot: P09467.5

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

果糖1，6-二***酶又称生长抑制蛋白17，是糖代谢过程中的关键酶，是一个典型的别构酶。
 
 产品图片
 Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; 

Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
Incubation: Anti-FBP1 Polyclonal Antibody, Unconjugated(bs-3980R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

 

Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
Incubation: Anti-FBP1 Polyclonal Antibody, Unconjugated(bs-3980R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

 

Antigen: bs-3980P, 0.2ug/100ul 
Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; 
Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; 
TMB(C-0024) staining; 
Read the data in MicroplateReader by 450nm.